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operon and begin using lactose after they have utilized up all of the preferred Electrical power supply (glucose).
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CAP features a characteristic helix-switch-helix motif construction that enables it to bind to successive big grooves on DNA. The 2 helices are reinforcing, Every creating a forty three° turn in the framework, having an In general 94° diploma transform inside the DNA.[four]
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repressor continues to be sure to the operator and stops transcription by RNA polymerase. Also, cAMP amounts are lower for the reason that glucose degrees are large, so CAP is inactive and cannot bind DNA.